Endocrine Abstracts

Introduction: The mutation of SDHB gene is associated with familial pheochromocytoma-paraganglioma syndrome (PPS). SDHB gene is located in locus 1p23–25 and encodes a subunit B of succinate dehydrogenase, which plays a key role in the respiratory chain and Krebs cycle.Pheochromocytoma in PPS usually produces norepinephrin. Even long term remission do not exclude relapse of the disease.We present a case of bilateral adrenal phe...

Introduction: We present the case of coincidence of pheochromocytoma and aderenocortical carcinoma at the same adrenal gland in patient with neurofibromatosis. That kind of tumors coincidence origin from different blastodermic layers is extremely rare.It is broadly known that pheochromocytoma is rare neoplasm, occurs in 0.1% of hypertensive individuals. Pheochromocytoma may occur sporadically or in certain familial syndromes, including multiple endocrine...